The market for RNA Polymerase I (Pol I) inhibitors is a nascent, highly specialized area of oncology drug discovery with strong biological rationale. Polymerase I is the enzyme that transcribes ...

Impact Therapeutics Inc. has disclosed new heteroaromatic and heterobicyclic compounds acting as Myt1 kinase (PKMYT1) inhibitors reported to be useful for the treatment of cancer. Impact Therapeutics ...

The ribosome is one of the most iconic machines in molecular biology—a complex structure that reads a recipe written in RNA to assemble amino acid building blocks into new proteins. Ting Zhu of ...

Response to radiation therapy in solitary fibrous tumor/hemangiopericytoma. This is an ASCO Meeting Abstract from the 2012 ASCO Annual Meeting I. This abstract does not include a full text component.

Pantoprazole affecting docetaxel resistance pathways via autophagy (PANDORA): a phase II trial in men with castration resistant prostate cancer (mCRPC). This is an ASCO Meeting Abstract from the 2016 ...

Potential first-in-class, and industry-leading DNA polymerase Theta (Polθ) inhibitor, ART6043 demonstrated an attractive tolerability profile, ...

Polymerase chain reaction (PCR) is a fundamental molecular biology tool that scientists use to amplify and analyze genetic material, such as DNA and RNA. PCR involves the enzymatic amplification of ...